2025

• New Generation Modified Azole Antifungals against Multidrug-Resistant Candida auris. Journal of Medicinal Chemistry. 2025;68(13):14054-71.
• C7-Substituted Quinolines as Potent Inhibitors of AdeG Efflux Pumps in Acinetobacter baumannii. ACS Infectious Diseases. 2025;11(3):626-38.
• An oral heme oxygenase inhibitor targets immunosuppressive perivascular macrophages in preclinical models of cancer. Science translational medicine. 2025;17(810):eads3085.
• P2Y14 receptor activation of platelets induces Ca2+ mobilization and Rho-GTPase-dependent motility that requires an interaction with P2Y1 receptors. British Journal of Pharmacology. 2025;182(13):2950-67.
• SARS-CoV-2 infection enhancement by amphotericin B: implications for disease management. Journal of Virology. 2025;99(7).
• Understanding the mechanisms of resistance to azole antifungals in Candida species. JAC-Antimicrobial Resistance. 2025;7(3).
• A novel DNA sequence-selective, guanine mono-alkylating ADC payload suitable for solid tumour treatment. RSC Medicinal Chemistry. 2025;16(7):3058-76.
• Anticancer, antimicrobial and molecular docking analysis of newly synthesized iodoquinazoline derivatives. AMB Express. 2025;15(1).
• Synthesis of novel pyrrolobenzodiazepine (PBD) C1-substituted monomers and dimers with DNA-binding activity and cytotoxicity. Bioorganic and Medicinal Chemistry Letters. 2025;119.
• Design, synthesis and evaluation of pyrrolobenzodiazepine (PBD)-based PROTAC conjugates for the selective degradation of the NF-κB RelA/p65 subunit. RSC Medicinal Chemistry. 2025.
• Brain distribution study of [14C]-Riluzole following intranasal administration in mice. International Journal of Pharmaceutics. 2025;670.
• Discovery of Phototoxic Metal Complexes with Antibacterial Properties via a Combinatorial Approach. Inorganic Chemistry. 2025;64(10):5113-21.

2024

• Stimulation of platelet P2Y1 receptors by different endogenous nucleotides leads to functional selectivity via biased signalling. British Journal of Pharmacology. 2024;181(4):564-79.
• Evaluation of Antibiotic Resistance Mechanisms in Gram-Positive Bacteria. Antibiotics. 2024;13(12).
• Exploring bias in platelet P2Y1 signalling: Host defence versus haemostasis. British Journal of Pharmacology. 2024;181(4):580-92.
• Synthesis of Pyrazoline derivatives, condensation of β-dicarbonyl compounds with isoniazid (INH), and their biological evaluation as multitarget anti-Alzheimer’ disease agents. Chemical Papers. 2024;78(3):2033-42.
• Bacterial Behaviour Analysis Through Image Segmentation Using Deep Learning Approaches. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); 2024.
• Introduction to ‘Medicinal Chemistry Small Molecule Probes’. RSC Chemical Biology. 2024;5(5):395-6.
• Isolation of a new iso-quinoline alkaloid and cytotoxicity studies of pure compounds and crude extracts of Ravenia spectabilis engl. Heliyon. 2024;10(14).
• Antiviral peptides inhibiting the main protease of SARS-CoV-2 investigated by computational screening and in vitro protease assay. Journal of Peptide Science. 2024;30(4).
• Anti-EGFR Antibody-Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024;30(15):3298-315.
• Nonclinical Evaluation of Single-Mutant E. coli Asparaginases Obtained by Double-Mutant Deconvolution: Improving Toxicological, Immune and Inflammatory Responses. International Journal of Molecular Sciences. 2024;25(11).
• Navigating fluoroquinolone resistance in Gram-negative bacteria: a comprehensive evaluation. JAC-Antimicrobial Resistance. 2024;6(4).

2023

• Isolation and Characterization of One New Natural Compound with Other Potential Bioactive Secondary Metabolites from Glycosmis cyanocarpa (Blume) Spreng. (Family: Rutaceae). Molecules. 2023;28(5).
• Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer’s disease. PLoS ONE. 2023;18(10 OCTOBER).
• Evaluation of Antibiotic Resistance Mechanisms in Gram-Negative Bacteria. Antibiotics. 2023;12(11).

2022

• Development and exploration of novel substituted thiosemicarbazones as inhibitors of aldose reductase via in vitro analysis and computational study. Scientific Reports. 2022;12(1).
• Factors influencing the choice of monoclonal antibodies for antibody–drug conjugates. Drug Discovery Today. 2022;27(1):354-61.
• DNA sequence-selective G-A cross-linking ADC payloads for use in solid tumour therapies. Communications Biology. 2022;5(1).
• Mechanistic insight into the repair of C8-linked pyrrolobenzodiazepine monomer-mediated DNA damage. RSC Medicinal Chemistry. 2022;32(2).
• Isolation and In Silico Prediction of Potential Drug-like Compounds with a New Dimeric Prenylated Quinolone Alkaloid from Zanthoxylum rhetsa (Roxb.) Root Extracts Targeted against SARS-CoV-2 (Mpro). Molecules. 2022;27(23).
• Development, Molecular Docking, and in Silico ADME Evaluation of Selective ALR2 Inhibitors for the Treatment of Diabetic Complications via Suppression of the Polyol Pathway. ACS Omega. 2022;7(30):26425-36.
• Efflux pumps in Mycobacterium tuberculosis and their inhibition to tackle antimicrobial resistance. Trends in Microbiology. 2022;30(1):57-68.
• Covalent DNA Binding Is Essential for Gram-Negative Antibacterial Activity of Broad Spectrum Pyrrolobenzodiazepines. Antibiotics. 2022;11(12).
• Identification and characterisation of G-quadruplex DNA-forming sequences in the Pseudomonas aeruginosa genome. RSC Chemical Biology. 2022;4(1):94-100.

2021

• Therapeutic intervention of COVID-19 by natural products: A population-specific survey directed approach. Molecules. 2021;26(4).
• Synthesis, microbiological evaluation and structure activity relationship analysis of linezolid analogues with different C5-acylamino substituents. Bioorganic and Medicinal Chemistry. 2021;49.
• Whole Genome Sequencing of Staphylococcus aureus SA-1199B Reveals Previously Unreported Mutations. International Journal of Antimicrobial Agents. 2021;57(1).
• Antibody–drug conjugates—a tutorial review. Molecules. 2021;26(10).
• Development of photoactivable phenanthroline-based manganese(I) CO-Releasing molecules (PhotoCORMs) active against ESKAPE bacteria and bacterial biofilms. European Journal of Medicinal Chemistry. 2021;213.
• Schiff bases of sulphonamides as a new class of antifungal agent against multidrug-resistant Candida auris. MicrobiologyOpen. 2021;10(4).
• A New Cyclohexanone Derivative from the Leaves of Bridelia stipularis. Chemistry of Natural Compounds. 2021;57(3):455-8.
• Indole alkaloids from the leaves of Ravenia spectabilis engl. with activity against pancreatic cancer cell line. Phytochemistry. 2021;186.
• KDM5B protein expressed in viable and fertile ΔARID mice exhibit no demethylase activity. International Journal of Oncology. 2021;59(5).
• Novel pyrrolobenzodiazepine benzofused hybrid molecules inhibit nuclear factor-κB activity and synergize with bortezomib and ibrutinib in hematologic cancers. Haematologica. 2021;106(4):958-67.
• Current trends and future approaches in small-molecule therapeutics for covid-19. Current Medicinal Chemistry. 2021;28(19):3803-24.

2020

• New Broad-Spectrum Antibiotics Containing a Pyrrolobenzodiazepine Ring with Activity against Multidrug-Resistant Gram-Negative Bacteria. Journal of Medicinal Chemistry. 2020;63(13):6941-58.
• N1-Benzofused Modification of Fluoroquinolones Reduces Activity against Gram-Negative Bacteria. ACS Omega. 2020;5(21):11923-34.
• Author Correction: The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition (Nature Communications, (2020), 11, 1, (1396), 10.1038/s41467-020-15163-6). Nature Communications. 2020;11(1).
• SAR based in-vitro anticholinesterase and molecular docking studies of nitrogenous progesterone derivatives. Steroids. 2020;158.
• Probing sulphamethazine and sulphamethoxazole based Schiff bases as urease inhibitors; synthesis, characterization, molecular docking and ADME evaluation. Bioorganic Chemistry. 2020;105.
• UPLC-based assay to assess the hydrophobicity of Antibody-Drug Conjugate (ADC) payloads. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2020;1146.
• The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition. Nature Communications. 2020;11(1).
• Antimicrobial Constituents from Machaerium Pers.: Inhibitory Activities and Synergism of Machaeriols and Machaeridiols against Methicillin-Resistant Staphylococcus aureus, Vancomycin-Resistant Enterococcus faecium, and Permeabilized Gram-Negative Pathogens. Molecules. 2020;25(24).
• Solid-state epimerisation and disproportionation of pilocarpine HCl: Why we need a 5-stage approach to validate melting point measurements for heat-sensitive drugs. International Journal of Pharmaceutics. 2020;574.
• Development of sulfonamide-based Schiff bases targeting urease inhibition: Synthesis, characterization, inhibitory activity assessment, molecular docking and ADME studies. Bioorganic Chemistry. 2020;102.
• A Cyclodextrin-Stabilized Spermine-Tagged Drug Triplex that Targets Theophylline to the Lungs Selectively in Respiratory Emergency. Advanced Therapeutics. 2020;3(12).
• Identifying the Responses from the Estrogen Receptor-Expressed MCF7 Cells Treated in Anticancer Drugs of Different Modes of Action Using Live-Cell FTIR Spectroscopy. ACS Omega. 2020;5(22):12698-706.
• Antibiotic-in-Cyclodextrin-in-Liposomes: Formulation Development and Interactions with Model Bacterial Membranes. Molecular Pharmaceutics. 2020;17(7):2354-69.
• Integron gene cassettes harboring novel variants of d-alanine-d-alanine ligase confer high-level resistance to d-cycloserine. Scientific Reports. 2020;10(1).

2019

• Author Correction: Mapping the Dynamic Functions and Structural Features of AcrB Efflux Pump Transporter Using Accelerated Molecular Dynamics Simulations (Scientific Reports, (2018), 8, 1, (10470), 10.1038/s41598-018-28531-6). Scientific Reports. 2019;9(1).
• Region-specific blood-brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease. Fluids and Barriers of the CNS. 2019;16(1).
• Noncytotoxic Pyrrolobenzodiazepine-Ciprofloxacin Conjugate with Activity against Mycobacterium tuberculosis. ACS Omega. 2019;4(25):20873-81.
• Towards identifying the mode of action of drugs using live-cell FTIR spectroscopy. Analyst. 2019;144(8):2725-35.
• Chapter 4: Pyrrolobenzodiazepines as Transcription Factor Inhibitors: An Overview. RSC Drug Discovery Series. 2019-January2019. p. 81-124.
• SmvA is an important efflux pump for cationic biocides in Klebsiella pneumoniae and other Enterobacteriaceae. Scientific Reports. 2019;9(1).
• Evaluating the level of nitroreductase activity in clinical Klebsiella pneumoniae isolates to support strategies for nitro drug and prodrug development. International Journal of Antimicrobial Agents. 2019;54(5):538-46.
• Antibiotic resistance breakers: Current approaches and future directions. FEMS Microbiology Reviews. 2019;43(5):490-516.
• Effectiveness of efflux pump inhibitors as biofilm disruptors and resistance breakers in gram- negative (ESKAPEE) bacteria. Antibiotics. 2019;8(4).
• Effects of Systematic Shortening of Noncovalent C8 Side Chain on the Cytotoxicity and NF-κB Inhibitory Capacity of Pyrrolobenzodiazepines (PBDs). Journal of Medicinal Chemistry. 2019;62(4):2127-39.

2018

• C8-Linked Pyrrolobenzodiazepine Monomers with Inverted Building Blocks Show Selective Activity against Multidrug Resistant Gram-Positive Bacteria. ACS Infectious Diseases. 2018;4(2):158-74.
• Synthesis, pharmacological evaluation and docking studies of progesterone and testosterone derivatives as anticancer agents. Steroids. 2018;136:22-31.
• Formation of a Novel C11-Acetone Adduct of a Pyrrolobenzodiazepine (PBD) with Loss of Cytotoxicity. Synlett. 2018;29(8):1112-6.
• Role of bacterial efflux pumps in biofilm formation. Journal of Antimicrobial Chemotherapy. 2018;73(8):2003-20.
• Diverse signalling of the platelet P2Y1 receptor leads to a dichotomy in platelet function. European Journal of Pharmacology. 2018;827:58-70.
• Mapping the dynamic functions and structural features of AcrB Efflux pump transporter using accelerated molecular dynamics simulations. Scientific Reports. 2018;8(1).
• Topical delivery of anthramycin II. Influence of binary and ternary solvent systems. European Journal of Pharmaceutical Sciences. 2018;121:59-64.
• Lawsonol, a New Bioactive Naphthoquinone Dimer From the Leaves of Lawsonia alba. Chemistry of Natural Compounds. 2018;54(1):26-9.
• Crispenes F and G, cis-Clerodane Furanoditerpenoids from Tinospora crispa, Inhibit STAT3 Dimerization. Journal of Natural Products. 2018;81(2):236-42.
• Fusaproliferin, a fungal mycotoxin, shows cytotoxicity against pancreatic cancer cell lines. Molecules. 2018;23(12).
• Antimicrobial molecules in the lung: Formulation challenges and future directions for innovation. Future Medicinal Chemistry. 2018;10(5):575-604.
• Methylene-linked bis-phenylbenzimidazoles-a new scaffold to target telomeric DNA/RNA hybrid duplex. Organic and Biomolecular Chemistry. 2018;16(24):4424-8.

2017

• Novel pyridyl nitrofuranyl isoxazolines show antibacterial activity against multiple drug resistant Staphylococcus species. Bioorganic and Medicinal Chemistry. 2017;25(15):3971-9.
• Topical delivery of anthramycin I. Influence of neat solvents. European Journal of Pharmaceutical Sciences. 2017;104:188-95.
• Fluoxetine and thioridazine inhibit efflux and attenuate crystalline biofilm formation by Proteus mirabilis. Scientific Reports. 2017;7(1).
• From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody–Drug Conjugates (ADCs). Angewandte Chemie – International Edition. 2017;56(2):462-88.
• Sequence-selective binding of C8-conjugated pyrrolobenzodiazepines (PBDs) to DNA. Biophysical Chemistry. 2017;230:53-61.
• The use of molecular dynamics simulations to evaluate the DNA sequence-selectivity of G–A cross-linking PBD–duocarmycin dimers. Bioorganic and Medicinal Chemistry Letters. 2017;27(1):102-8.
• In Silico and in Vitro Screening for P-Glycoprotein Interaction with Tenofovir, Darunavir, and Dapivirine: An Antiretroviral Drug Combination for Topical Prevention of Colorectal HIV Transmission. Molecular Pharmaceutics. 2017;14(8):2660-9.
• Computational Study Reveals the Molecular Mechanism of the Interaction between the Efflux Inhibitor PAβN and the AdeB Transporter from Acinetobacter baumannii. ACS Omega. 2017;2(6):3002-16.
• Cytotoxic Naphthoquinone and Azaanthraquinone Derivatives from an Endophytic Fusarium solani. Journal of Natural Products. 2017;80(4):1173-7.
• Triaryl Benzimidazoles as a New Class of Antibacterial Agents against Resistant Pathogenic Microorganisms. Journal of Medicinal Chemistry. 2017;60(14):6045-59.

2016

• Current advances in developing inhibitors of bacterial multidrug efflux pumps. Current Medicinal Chemistry. 2016;23(10):1062-81.
• Covalent bonding of pyrrolobenzodiazepines (PBDs) to terminal guanine residues within duplex and hairpin DNA fragments. PLoS ONE. 2016;11(4).
• Recent advances in targeting the telomeric G-quadruplex DNA sequence with small molecules as a strategy for anticancer therapies. Future Medicinal Chemistry. 2016;8(11):1259-90.
• An overview of bacterial efflux pumps and computational approaches to study efflux pump inhibitors. Future Medicinal Chemistry. 2016;8(2):195-210.

2015

• Synthesis and cytotoxicity of 4-(2-Adamantyl)phenylalkylamines. Letters in Organic Chemistry. 2015;12(5):319-23.
• Novel 1-(2-aryl-2-adamantyl)piperazine derivatives with antiproliferative activity. European Journal of Medicinal Chemistry. 2015;93:281-90.
• Effect of hairpin loop structure on reactivity, sequence preference and adduct orientation of a DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour agent. Organic and Biomolecular Chemistry. 2015;13(13):4031-40.
• Crispene E, a cis-clerodane diterpene inhibits STAT3 dimerization in breast cancer cells. Organic and Biomolecular Chemistry. 2015;13(13):3882-6.
• Topical therapies for skin cancer and actinic keratosis. European Journal of Pharmaceutical Sciences. 2015;77:279-89.

2014

• Pyrrolobenzodiazepines (PBDs) do not bind to DNA G-quadruplexes. PLoS ONE. 2014;9(8).
• Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition. ACS Chemical Biology. 2014;9(10):2432-40.
• Tetracycline analogues with a selective inhibitory effect on HIF-1α. MedChemComm. 2014;5(7):923-6.

2013

• Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography. FEBS Letters. 2013;587(7):833-9.
• Investigation of the protein alkylation sites of the STAT3:STAT3 inhibitor Stattic by mass spectrometry. Bioorganic and Medicinal Chemistry Letters. 2013;23(16):4719-22.
• GC-Targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models. Journal of Medicinal Chemistry. 2013;56(7):2911-35.

2012

• Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates. Journal of Antimicrobial Chemotherapy. 2012;67(7):1683-96.
• Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries. Bioorganic and Medicinal Chemistry Letters. 2012;22(8):3006-10.
• The prenylated dioxopiperazine alkaloid Cristatin A has selective telomeric DNA G-quadruplex stabilising properties. Chemical Communications. 2012;48(70):8760-2.

2011

• Observation of a single-stranded DNA/pyrrolobenzodiazepine adduct. Journal of the American Chemical Society. 2011;133(48):19376-85.
• Observation of the reversibility of a covalent pyrrolobenzodiazepine (PBD) DNA adduct by HPLC/MS and CD spectroscopy. Organic and Biomolecular Chemistry. 2011;9(5):1632-41.
• The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus. Journal of Antimicrobial Chemotherapy. 2011;66(5):985-96.
• Effect of base sequence on the DNA cross-linking properties of pyrrolobenzodiazepine (PBD) dimers. Nucleic Acids Research. 2011;39(13):5800-12.

2010

• A novel small-molecule inhibitor of IL-6 signalling. Bioorganic and Medicinal Chemistry Letters. 2010;20(23):7029-32.
• DNA sequence preference and adduct orientation of pyrrolo[2,1- c ][1,4]benzodiazepine antitumor agents. ACS Medicinal Chemistry Letters. 2010;1(8):427-32.

2009

• Effect of microwave irradiation on covalent ligand-DNA interactions. Chemical Communications. 2009(20):2875-7.
• Observation of a dynamic equilibrium between DNA hairpin and duplex forms of covalent adducts of a minor groove binding agent. Chemical Communications. 2009(2):227-9.
• The pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links. Journal of the American Chemical Society. 2009;131(38):13756-66.
• Biaryl polyamides as a new class of DNA quadruplex-binding ligands. Chemical Communications. 2009(27):4097-9.

2008

• Preliminary cytotoxicity screening of some medicinal plants of Bangladesh. Dhaka University Journal of Pharmaceutical Sciences. 2008;7(1):47-52.

2007

• Antinociceptive activity of Vitis trifolia. Dhaka University Journal of Pharmaceutical Sciences. 2007;6(2):129-30.

2006

• Stereochenols A and B, two quinones from Stereospermum chelonoides. Phytochemistry. 2006;67(24):2663-5.

2004

• Antibacterial activity and cytotoxicity of extractives from Ravenia spectabilis. Fitoterapia. 2004;75(5):510-3.
• Cytotoxicity and antibacterial activity of extractives from Wedelia calendulacea. Fitoterapia. 2004;75(3-4):355-9.

2000

• Evaluation of antitumor activity of some medicinal plants of Bangladesh by potato disk bioassay. Fitoterapia. 2000;71(5):547-52.